Osteoarthritis (OA), also known as degenerative joint disease (DJD), is the most common form of arthritis in the United States.1 Although OA can occur in any synovial joint in the body, it most commonly affects the knees, hips, and hands. OA is the
leading cause of disability in elderly persons and affects approximately 14% of all adults aged ≥25 years; >12 million of
those affected are aged ≥65 years. Women are more commonly affected than men.2 OA is associated with remarkable personal, health, and economic costs, including 400,000 hospitalizations and an estimated
$8 billion for knee and hip replacements annually.1 The prevalence of OA is expected to increase in the coming years as risk factors, such as an aging population and obesity,
become more prevalent.